Taiwan Agricultural Chemicals and Toxic Substances

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Toxicology Testing Services

Toxicology Testing Services

  • Hit: 1492
  • Source: TACTRI / COA
  • Date: 2015/01/19

Toxicology Testing Services

Test
Reference
1.      Acute Oral Toxicity
--- Up and Down Procedure
(1)       Organization for Economic Cooperation and Development. 2008. OECD Guidelines for the Testing of Chemicals. Guideline 425: Acute Oral Toxicity-Up-and-Down-Procedure.
(2)       Environmental Protection Agency. 2002. Health Effects Test Guidelines OCSPP 870.1100: Acute Oral Toxicity, EPA 712-C-02-190.
2.      Acute Dermal Toxicity
(1)   Organization for Economic Cooperation and Development. 1987. OECD Guidelines for the Testing of Chemicals. Guideline 402: Acute Dermal Toxicity.
(2)   Environmental Protection Agency. 1998. Health Effects Test Guidelines OCSPP 870.1200: Acute Dermal Toxicity, EPA 712–C–98–192.
3.      Acute Inhalation Toxicity
(1)   Organization for Economic Cooperation and Development. 2009. OECD Guidelines for the Testing of Chemicals. Guideline 403: Acute Inhalation Toxicity.
(2)   Environmental Protection Agency. 1998. Health Effects Test Guidelines OCSPP 870.1300: Acute Inhalation Toxicity, EPA 712-C-98-193.
4.      Acute Oral Toxicity and Pathogenicity study
Environmental Protection Agency. 1996. Health Effects Test Guidelines OCSPP 885.3050: Acute Oral Toxicity/Pathogenicity, EPA 712-C-96–315.
5.      Acute Pulmonary Toxicity and Pathogenicity Study
Environmental Protection Agency. 1996. Health Effects Test Guidelines OCSPP 885.3150: Acute Pulmonary Toxicity/Pathogenicity, EPA 712-C-96–317.
6.      Acute Eye Irritation
(1)       Organization for Economic Cooperation and Development. 2012. OECD Guidelines for the Testing of Chemicals. Guideline 405: Acute Eye Irritation/Corrosion.
(2)       Environmental Protection Agency. 1998. Health Effects Test Guidelines OCSPP 870.2400: Acute Eye Irritation, EPA 712-C-98-195.
7.      Acute Dermal Irritation
(1)       Organization for Economic Cooperation and Development. 2002. OECD Guidelines for the Testing of Chemicals. Guideline 404: Acute Dermal Irritation/Corrosion.
(2)       Environmental Protection Agency. 1998. Health Effects Test Guidelines OCSPP 870.2500: Acute Dermal Irritation, EPA 712-C-98-196.
8.      Skin Sensitization
---Local Lymph Node Assay
Organization for Economic Cooperation and Development. 2010. OECD Guidelines for the Testing of Chemicals. Guideline 442B: Skin Sensitization: Local Lymph Node Assay: BrdU-ELISA.
9.      Skin Sensitization
--- Buehler test
(1)       Organization for Economic Cooperation and Development. 1992. OECD Guidelines for the Testing of Chemicals. Guideline 406: Skin Sensitization.
(2)       Environmental Protection Agency. 2003. Health Effects Test Guidelines OCSPP 870.2600: Acute Dermal Irritation, EPA 712-C-03-197.
10. Mutagenicity Studies
--- Bacterial Gene Reverse Mutation Assay
(1)       Organization for Economic Cooperation and Development. 1997. OECD Guidelines for the Testing of Chemicals. Guideline 471: Bacterial Reverse Mutation Test.
(2)       Environmental Protection Agency. 1998. Health Effects Test Guidelines OCSPP 870.5100: Bacterial Reverse Mutation Test, EPA 712-C-98-247.
11. Mutagenicity Studies
--Rec Assay
Environmental Protection Agency. 1998.  Health Effects Test Guidelines: OPPTS 870.5500: Bacterial DNA damage or repair tests, EPA 712-C-98-229.
12. Mutagenicity Studies
--- Sister Chromatid Exchange Assay in CHO Cell
(1)       Organization for Economic Cooperation and Development. 1986. OECD Guidelines for the Testing of Chemicals. Guideline 479: In vitro sister chromatid exchange assay in mammalian cells.
(2)       Environmental Protection Agency. 1998.Health Effects Test Guidelines. OCSPP 870.5900: In vitro sister chromatid exchange assay, EPA 712-C-98-234. 
13. Mutagenicity Studies
--- In Vitro Mammalian Cell Micronucleus Test
Organization for Economic Cooperation and Development. 2010. OECD Guidelines for the Testing of Chemicals. Guideline 487: In vitro Mammalian Cell Micronucleus Test.
14. Mutagenicity Studies
---Mouse erythrocyte micronucleus test
(1)       Organization for Economic Cooperation and Development. 1997. OECD Guidelines for the Testing of Chemicals. Guideline 474: Mammalian Erythrocyte Micronucleus Test.
(2)       Environmental Protection Agency. 1998. Health Effects Test Guidelines OCSPP 870.5395: Mammalian Erythrocyte Micronucleus Test, EPA 712-C-98-226.
15. Rodenticide Toxicity Test
(1)       European and Mediterranean Plant Protection Organization. 1998. Guidelines for Biological Evaluation of the Toxicity and Acceptability of Rodenticides and Rodenticide Preparations, pp. 1-32.
(2)       World Health Organization. 2006. Pesticides and Their Application—For the Control of vectors and Pests of Public Health Importance, pp. 92-97.
16. Aquatic Toxicity
--- Acute Zebrafish toxicity study
Organization for Economic Cooperation and Development. 1992. OECD Guidelines for the Testing of Chemicals. Guideline 203: Fish, Acute Toxicity Test.
17. Aquatic Toxicity
--- Acute Daphnia toxicity study
Organization for Economic Cooperation and Development. 2004. OECD Guidelines for the Testing of Chemicals. Guideline 202: Daphnia sp., Acute Immobilization Test.
18. Prenatal Development Toxicity Study in Rats
(1)       Organization for Economic Cooperation and Development. 2001. OECD Guidelines for the Testing of Chemicals. Guideline 414: Prenatal Development Toxicity Study.
(2)       Environmental Protection Agency. 1998. Health Effects Test Guidelines OCSPP 870.3700: Prenatal Developmental Toxicity Study, EPA 712-C-98-207.